Ama-sulfide emanzini athambekele ekuqhekekeni kwamanzi, akhiphe i-H₂S emoyeni. Ukuphefumula inani elikhulu le-H₂S kungabangela ngokushesha isicanucanu, ukuhlanza, ubunzima bokuphefumula, ukuminyana, kanye nemiphumela emibi kakhulu enobuthi. Ukuchayeka ekugxilweni komoya okungu-15–30 mg/m³ kungaholela ekugugulekeni kwe-conjunctivitis kanye nomonakalo ku-optic nerve. Ukuphefumula isikhathi eside kwe-H₂S kungasebenzisana ne-cytochrome, i-oxidase, izibopho ze-disulfide (-SS-) kumaprotheni nama-amino acid, kuphazamise izinqubo zokuxiliswa kwamaseli futhi kubangele i-hypoxia yamaseli, okungaba yingozi empilweni.

Iqoqo ngalinye le-sodium sulfide lihlolwa izingxenye futhi lihlolwe ukungcola ukuze kuqedwe ingozi yokungcola okuvela emthonjeni. Chofoza lapha ukuze uthole izinsizakalo zobungcweti.